Pub. Date : 2005 May 13
PMID : 15737992
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins. | Phosphotyrosine | Cbl proto-oncogene | Homo sapiens |
| 2 | The previously derived consensus sequence for phosphotyrosine recognition by the Cbl TKB domain is NXpY(S/T)XXP (X denotes lesser residue preference), wherein specificity is conferred primarily by residues C-terminal to the phosphotyrosine. | Phosphotyrosine | Cbl proto-oncogene | Homo sapiens |
| 3 | The previously derived consensus sequence for phosphotyrosine recognition by the Cbl TKB domain is NXpY(S/T)XXP (X denotes lesser residue preference), wherein specificity is conferred primarily by residues C-terminal to the phosphotyrosine. | Phosphotyrosine | Cbl proto-oncogene | Homo sapiens |
| 4 | These studies reveal a novel mode of phosphopeptide interaction with the Cbl TKB domain, in which N-terminal residues distal to the phosphotyrosine directly contact residues of the four-helix bundle of the TKB domain. | Phosphotyrosine | Cbl proto-oncogene | Homo sapiens |