Title : Regulation of TGF-alpha expression in human keratinocytes: PKC-dependent and -independent pathways.

Pub. Date : 1992 May

PMID : 1572907






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Tyrosine phosphorylation and TGF-alpha mRNA accumulation in response to EGF and TGF-alpha were both inhibited by a monoclonal antibody against the EGF receptor and by the EGF receptor tyrosine kinase inhibitor RG50864, demonstrating the involvement of the tyrosine kinase activity of the receptor in TGF-alpha autoinduction. Tyrosine ret proto-oncogene Homo sapiens