Title : Monoamine transporter inhibitors and norepinephrine reduce dopamine-dependent iron toxicity in cells derived from the substantia nigra.

Pub. Date : 2005 Mar

PMID : 15715653






1 Functional Relationships(s)
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1 However, 100 microm Fe(III)-dopamine in the presence of 100 microm dicoumarol, an inhibitor of DT-diaphorase, induced toxicity (44% cell death; p < 0.001), which was inhibited by 2 microm nomifensine, 30 microm reboxetine and 2 mm norepinephrine. Dicumarol NAD(P)H quinone dehydrogenase 1 Rattus norvegicus