Title : Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction.

Pub. Date : 2005 Mar 1

PMID : 15713419






1 Functional Relationships(s)
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1 A series of 2-N-alkyl-3-aryl-3-alkoxyisoindolinones has been synthesised and evaluated as inhibitors of the MDM2-p53 interaction. 2-n-alkyl-3-aryl-3-alkoxyisoindolinones MDM2 proto-oncogene Homo sapiens