Title : Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: consequences for FK506 assimilation.

Pub. Date : 2005 Mar

PMID : 15698457






3 Functional Relationships(s)
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1 Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: consequences for FK506 assimilation. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 BACKGROUND: Cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (PGP) are important determinants of the oral bioavailability and clearance of tacrolimus. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
3 BACKGROUND: Cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (PGP) are important determinants of the oral bioavailability and clearance of tacrolimus. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens