Pub. Date : 2005 Jun
PMID : 15687373
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Loperamide is a strong inhibitor of CES2, with a K(i) of 1.5 muM, but it only weakly inhibits CES1A1 (IC(50) = 0.44 mM). | Loperamide | carboxylesterase 2 | Homo sapiens |
| 2 | Inhibition of CES2 in the gastrointestinal tract by loperamide may reduce local formation of 5"-DFCR. | Loperamide | carboxylesterase 2 | Homo sapiens |