Title : The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation.

Pub. Date : 2005 May 1

PMID : 15683363






1 Functional Relationships(s)
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Protein Name
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1 Mutation of a cluster of three threonine and one serine residue at the extreme C-terminus of the receptor greatly reduced interaction and abolished co-internalization of beta-arrestin-2-GFP (green fluorescent protein). Threonine arrestin beta 2 Homo sapiens