Title : Biotin deficiency stimulates survival pathways in human lymphoma cells exposed to antineoplastic drugs.

Pub. Date : 2005 Feb

PMID : 15681168






2 Functional Relationships(s)
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1 If cells were treated with antineoplastic agents (taxol, doxorubicin or vinblastine), nuclear translocation of two NF-kappaB proteins (p50 and p65) was >25% greater in biotin-deficient compared with biotin-supplemented cells. Doxorubicin nuclear factor kappa B subunit 1 Homo sapiens
2 If cells were treated with antineoplastic agents (taxol, doxorubicin or vinblastine), nuclear translocation of two NF-kappaB proteins (p50 and p65) was >25% greater in biotin-deficient compared with biotin-supplemented cells. Doxorubicin nuclear factor kappa B subunit 1 Homo sapiens