Title : Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.

Pub. Date : 2005 Feb 15

PMID : 15670581






1 Functional Relationships(s)
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1 We found that the activities of hRRM2/hRRM1 and p53R2/hRRM1 were decreased by hydroxyurea in a dose-dependent manner. Hydroxyurea ribonucleotide reductase regulatory subunit M2 Homo sapiens