Protein Name ribonucleotide reductase regulatory subunit M2
Organism Homo sapiens
Gene ID 6241
Gene Symbol

RRM2

UniProt P31350 (RIR2_HUMAN)
Relationships Total Number of functionally related compound(s) : 249
Total Number of Articles : 268
Description

ribonucleotide reductase regulatory subunit M2

Gene Summary

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]

synonyms
  • ribonucleoside-diphosphate reductase subunit M2
  • ribonucleotide reductase M2 polypeptide
  • ribonucleotide reductase small chain
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Properties