Title : ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism.

Pub. Date : 2004 Nov

PMID : 15666826






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both sphingosine and S1P were found to increase endogenous CYP17 mRNA and activate the transcriptional activity of CYP17-luciferase reporter constructs. Sphingosine cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Both sphingosine and S1P were found to increase endogenous CYP17 mRNA and activate the transcriptional activity of CYP17-luciferase reporter constructs. Sphingosine cytochrome P450 family 17 subfamily A member 1 Homo sapiens