Title : The importance of IRS-1 Gly972Arg polymorphism in evaluating the response to metformin treatment in polycystic ovary syndrome.

Pub. Date : 2005 May

PMID : 15665022






2 Functional Relationships(s)
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1 RESULTS: Metformin had differential effects on fasting insulin levels, insulin resistance as demonstrated by homeostasis model assessment (HOMA), LH, total testosterone, dehydroepiandrosterone sulphate and free testosterone index on the basis of IRS genotype. Metformin isoleucyl-tRNA synthetase 1 Homo sapiens
2 CONCLUSION: There was a differential effect of metformin therapy in PCOS women on the basis of IRS genotype. Metformin isoleucyl-tRNA synthetase 1 Homo sapiens