Pub. Date : 2005 Feb
PMID : 15663900
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The tyrosine phosphorylation of ERK1/2 was examined by immunoprecipitation techniques using anti-phospho-tyrosine antibodies. | Tyrosine | mitogen activated protein kinase 3 | Rattus norvegicus |
| 2 | The tyrosine phosphorylation of ERK1/2 was examined by immunoprecipitation techniques using anti-phospho-tyrosine antibodies. | Tyrosine | mitogen activated protein kinase 3 | Rattus norvegicus |
| 3 | Furthermore immunoprecipitation studies showed that both onychin and genistein markedly inhibited the tyrosine phosphorylation of ERK1/2 induced by 10% NCS. | Tyrosine | mitogen activated protein kinase 3 | Rattus norvegicus |
| 4 | CONCLUSION: Onychin inhibits the proliferation of VSMCs through G1 phase cell cycle arrest by decreasing the tyrosine phosphorylation of ERK1/2, and the expression of cyclin D1 and cyclin E, and sequentially inhibiting Rb phosphorylation. | Tyrosine | mitogen activated protein kinase 3 | Rattus norvegicus |