Pub. Date : 2005 Apr
PMID : 15661813
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The objective of this study was to examine the ability of dietary polyphenols to inhibit cytochrome P450 (CYP) 1A1 expression and activity and benzo[a]pyrene (BaP) DNA binding, with the main emphasis on prevention of chemical-induced hepatic carcinogenesis. | Polyphenols | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
2 | Second, we screened 25 polyphenols with highly varying chemical structures for maximum ability to inhibit CYP1A1 activity in the Hep G2 cells. | Polyphenols | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |