Title : The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro.

Pub. Date : 2005 Feb

PMID : 15655515






1 Functional Relationships(s)
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1 NO and L-citrulline production by EA.hy926 cells rose up to 1.7-fold of control levels after stimulation with genistein for 48-96 h. From these results, we conclude that the suggested positive effects of soy isoflavones on vascular reactivity may be indeed mediated via a long-term effect on the eNOS system. Genistein nitric oxide synthase 3 Homo sapiens