Pub. Date : 2005
PMID : 15652995
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates. | Modafinil | hypocretin | Mus musculus |
2 | Fos protein immunohistochemistry has previously demonstrated that orexin neurons are activated after modafinil administration, and it has been hypothesized that the wakefulness-promoting properties of modafinil might therefore be mediated by the neuropeptide. | Modafinil | hypocretin | Mus musculus |
3 | Fos protein immunohistochemistry has previously demonstrated that orexin neurons are activated after modafinil administration, and it has been hypothesized that the wakefulness-promoting properties of modafinil might therefore be mediated by the neuropeptide. | Modafinil | hypocretin | Mus musculus |
4 | Surprisingly, modafinil more effectively increased wakefulness time in orexin-/- mice than in the wild-type mice. | Modafinil | hypocretin | Mus musculus |
5 | Modafinil administration only partly compensated for this attention deficit in the orexin null mice. | Modafinil | hypocretin | Mus musculus |