Title : Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation.

Pub. Date : 2005 Feb 25

PMID : 15652497






1 Functional Relationships(s)
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1 Inhibition of Cdc25 phosphatases in rat liver epithelial cells employing a 1,4-naphthoquinone-based inhibitor, NSC95397, induced cell cycle arrest, tyrosine phosphorylation of the epidermal growth factor receptor (EGFR), and activation of extracellular signal-regulated kinases ERK-1 and -2. Tyrosine epidermal growth factor receptor Rattus norvegicus