Title : Histamine H1 receptor antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/I kappa B/NF-kappa B signal cascades.

Pub. Date : 2005 Feb 1

PMID : 15652235






1 Functional Relationships(s)
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1 PD98059 preferentially inhibited GM-CSF production whereas BAY 11-8702 prevented IL-8 and IL-6 production. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one colony stimulating factor 2 Homo sapiens