Title : Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation.

Pub. Date : 2005 Jan 10

PMID : 15642120






3 Functional Relationships(s)
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1 The molecular mechanisms responsible for these effects are unclear, and there are conflicting reports on the effects of CLA on peroxisomal proliferator-activated receptor-gamma (PPARgamma) activation and expression. Linoleic Acids, Conjugated peroxisome proliferator activated receptor gamma Mus musculus
2 The molecular mechanisms responsible for these effects are unclear, and there are conflicting reports on the effects of CLA on peroxisomal proliferator-activated receptor-gamma (PPARgamma) activation and expression. Linoleic Acids, Conjugated peroxisome proliferator activated receptor gamma Mus musculus
3 CLA enriched with its trans-10, cis-12 isomer, but not with its cis-9, trans-11 isomer, stimulated PPARgamma-mediated reporter gene activity; both isomers stimulated PPARalpha-mediated reporter gene activity. Linoleic Acids, Conjugated peroxisome proliferator activated receptor gamma Mus musculus