Title : Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

Pub. Date : 2005 Jan 5

PMID : 15634780






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Overexpression of UCP2 decreased reactive oxygen species (ROS) production, which was measured using dihydroethidium because it is specifically oxidized to fluorescent ethidium by the superoxide anion, whereas mice lacking UCP2 exhibited increased ROS relative to wild-type controls. Ethidium uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus