Title : Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.

Pub. Date : 2004 Nov

PMID : 15632311






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclin A/Cdk2 complexes phosphorylated serine residues on pRb crucial for the G1 to S phase transition in proliferating HepG2 cells, and HGF treatment inhibited the phosphorylation. Serine RB transcriptional corepressor 1 Homo sapiens