Title : SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.

Pub. Date : 2005 Mar 18

PMID : 15632193






3 Functional Relationships(s)
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Protein Name
Organism
1 The SIR2 family of nicotinamide adenosine dinucleotide (NAD)-dependent deacetylases modulates diverse biological functions in different species, including longevity, apoptosis, cell cycle exit, and cellular differentiation. nadide sirtuin 1 Homo sapiens
2 Herein, SIRT1 physically interacted with and repressed p300 transactivation, requiring the NAD-dependent deacetylase activity of SIRT1. nadide sirtuin 1 Homo sapiens
3 Herein, SIRT1 physically interacted with and repressed p300 transactivation, requiring the NAD-dependent deacetylase activity of SIRT1. nadide sirtuin 1 Homo sapiens