Title : Progesterone antagonists: tumor-inhibiting potential and mechanism of action.

Pub. Date : 1992 Mar

PMID : 1562510






2 Functional Relationships(s)
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1 Although the roles of progesterone and the progesterone receptor in control of cell growth remain unclear, it was found in progesterone receptor positive mammary carcinoma cell lines that the antiprogestin, Mifepristone, had an inhibitory effect on cell growth and a growth-inhibiting action on the DMBA-induced mammary carcinoma of the rat. Mifepristone progesterone receptor Rattus norvegicus
2 Although the roles of progesterone and the progesterone receptor in control of cell growth remain unclear, it was found in progesterone receptor positive mammary carcinoma cell lines that the antiprogestin, Mifepristone, had an inhibitory effect on cell growth and a growth-inhibiting action on the DMBA-induced mammary carcinoma of the rat. Mifepristone progesterone receptor Rattus norvegicus