Pub. Date : 2005 May
PMID : 15625084
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In transiently transfected MDCK-C7 cells, stimulation with forskolin induced translocation of AQP2-WT to the plasma membrane. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 2 | Treatment of AQP2-WT cells with the PKA inhibitor H-89 following forskolin stimulation resulted in internalization of AQP2-WT. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 3 | Treatment of AQP2-WT cells with the PKA inhibitor H-89 following forskolin stimulation resulted in internalization of AQP2-WT. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 4 | Moreover, H-89 treatment of AQP2-S256D (mimicking constitutively phosphorylated AQP2 and hence localized to the plasma membrane) resulted in redistribution of AQP2-S256D to intracellular vesicles, even in the presence of forskolin. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 5 | Moreover, H-89 treatment of AQP2-S256D (mimicking constitutively phosphorylated AQP2 and hence localized to the plasma membrane) resulted in redistribution of AQP2-S256D to intracellular vesicles, even in the presence of forskolin. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 6 | Moreover, H-89 treatment of AQP2-S256D (mimicking constitutively phosphorylated AQP2 and hence localized to the plasma membrane) resulted in redistribution of AQP2-S256D to intracellular vesicles, even in the presence of forskolin. | Colforsin | aquaporin 2 | Rattus norvegicus |
| 7 | Both PGE2 and dopamine stimulation induced endocytosis of AQP2-WT and AQP2-S256D, respectively, in forskolin-stimulated cells. | Colforsin | aquaporin 2 | Rattus norvegicus |