Title : Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra.

Pub. Date : 2005 Mar

PMID : 15625078






1 Functional Relationships(s)
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1 To test the involvement of dopamine (DA) in this degeneration induced by LPS, we treated albino Wistar rats with different concentrations of alpha-methyl-p-tyrosine (alpha-MPT), an inhibitor of tyrosine hydroxylase (TH) activity. alpha-Methyltyrosine tyrosine hydroxylase Rattus norvegicus