Pub. Date : 2003
PMID : 15618735
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hitherto three variant forms of ABCG2 have been documented on the basis of their amino acid moieties (i.e., Arg, Gly, and Thr) at the position 482. | Glycine | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |
| 2 | The ATPase activity of the plasma membrane expressing ABCG2 (Gly-482) was significantly enhanced by prazosin. | Glycine | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |
| 3 | In contrast, ABCG2 (Arg-482) transports [(3)H]methotrexate in an ATP-dependent manner; however, no transport activity was observed with the other variants (Gly-482 and Thr-482). | Glycine | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |