Title : Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells.

Pub. Date : 2005 Jan 20

PMID : 15617835






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 MRP1 functions as an efflux pump of drugs, primarily those conjugated to glutathione (GSH). Glutathione ATP binding cassette subfamily B member 1 Homo sapiens
2 MRP1 functions as an efflux pump of drugs, primarily those conjugated to glutathione (GSH). Glutathione ATP binding cassette subfamily B member 1 Homo sapiens
3 Decreases in the intracellular concentration of GSH have been shown to enhance the response of MRP1-overexpressing cells to MRP1-substrate drugs by limiting the available drug-GSH conjugates. Glutathione ATP binding cassette subfamily B member 1 Homo sapiens
4 Decreases in the intracellular concentration of GSH have been shown to enhance the response of MRP1-overexpressing cells to MRP1-substrate drugs by limiting the available drug-GSH conjugates. Glutathione ATP binding cassette subfamily B member 1 Homo sapiens
5 Decreases in the intracellular concentration of GSH have been shown to enhance the response of MRP1-overexpressing cells to MRP1-substrate drugs by limiting the available drug-GSH conjugates. Glutathione ATP binding cassette subfamily B member 1 Homo sapiens
6 Decreases in the intracellular concentration of GSH have been shown to enhance the response of MRP1-overexpressing cells to MRP1-substrate drugs by limiting the available drug-GSH conjugates. Glutathione ATP binding cassette subfamily B member 1 Homo sapiens