Title : Platelet serotonin uptake and paroxetine binding among allelic genotypes of the serotonin transporter in alcoholics.

Pub. Date : 2005 Jan

PMID : 15610939






3 Functional Relationships(s)
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1 Platelet serotonin uptake and paroxetine binding among allelic genotypes of the serotonin transporter in alcoholics. Paroxetine solute carrier family 6 member 4 Homo sapiens
2 Concentration curves of [3H]5-HT and [3H]paroxetine were used to quantify the equilibrium constant (Km) and maximum 5-HT uptake rate (Vmax) for 5-HTT uptake into intact platelets and the dissociation constant (Kd) and maximum specific binding density (Bmax) for paroxetine binding to platelet membranes, respectively. Paroxetine solute carrier family 6 member 4 Homo sapiens
3 Concentration curves of [3H]5-HT and [3H]paroxetine were used to quantify the equilibrium constant (Km) and maximum 5-HT uptake rate (Vmax) for 5-HTT uptake into intact platelets and the dissociation constant (Kd) and maximum specific binding density (Bmax) for paroxetine binding to platelet membranes, respectively. Paroxetine solute carrier family 6 member 4 Homo sapiens