Title : Anti-proliferative and proapoptotic effects of (-)-epigallocatechin-3-gallate on human melanoma: possible implications for the chemoprevention of melanoma.

Pub. Date : 2005 Apr 20

PMID : 15609335






1 Functional Relationships(s)
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1 Furthermore, our data demonstrated that EGCG treatment resulted in a significant, dose-dependent decrease in cyclin D1 and cdk2 protein levels and induction of cyclin kinase inhibitors (ckis) p16INK4a, p21WAF1/CIP1 and p27KIP1. epigallocatechin gallate cyclin dependent kinase 2 Homo sapiens