Title : Potent Kv1.3 inhibitors from correolide-modification of the C18 position.

Pub. Date : 2005 Jan 17

PMID : 15603971






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Potent Kv1.3 inhibitors from correolide-modification of the C18 position. correolide potassium voltage-gated channel subfamily A member 3 Homo sapiens
2 Correolide (1), a pentacyclic natural product, is a potent and selective Kv1.3 channel blocker. correolide potassium voltage-gated channel subfamily A member 3 Homo sapiens
3 Simplification of correolide via removal of its E-ring generates enone 4, whose modification produced a new series of tetracyclic Kv1.3 blockers. correolide potassium voltage-gated channel subfamily A member 3 Homo sapiens