Title : Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex.

Pub. Date : 2004 Dec 14

PMID : 15589152






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Loss of a functional RMX complex (Rad50/Mre11/Xrs2) or a mutation in the Rad50 Zn-hook structure resulted in DNA ends being dispersed in approximately 10%-20% of cells. 3-Chloro-4-(dichloromethyl)-2(5H)-furanone MRE11 homolog, double strand break repair nuclease Homo sapiens