Title : Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma.

Pub. Date : 2004 Dec

PMID : 15578089






1 Functional Relationships(s)
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1 In vitro studies have suggested that PPARs exert antiatherogenic effects by inhibiting the expression of proinflammatory genes and enhancing cholesterol efflux via activation of the liver X receptor-ABCA1 (LXR-ABCA1) pathway. Cholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus