Pub. Date : 2004 Nov
PMID : 15542045
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bone as a source of FGF23: regulation by phosphate? | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 2 | The identification of FGF23 as a factor involved in several disorders of phosphate regulation and of PHEX as the gene mutated in X-linked Hypophosphatemic Rickets indicates that both these genes may be involved in phosphate homeostasis, although their physiological roles are unclear. | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 3 | The identification of FGF23 as a factor involved in several disorders of phosphate regulation and of PHEX as the gene mutated in X-linked Hypophosphatemic Rickets indicates that both these genes may be involved in phosphate homeostasis, although their physiological roles are unclear. | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 4 | Expression of FGF23 mRNA in human osteoblast-like bone cells, quantitated by real-time RT-PCR, increased with increasing extracellular phosphate and was 2-fold higher in cells treated with 2 mM extracellular phosphate compared to 0 mM phosphate treatment. | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 5 | Expression of FGF23 mRNA in human osteoblast-like bone cells, quantitated by real-time RT-PCR, increased with increasing extracellular phosphate and was 2-fold higher in cells treated with 2 mM extracellular phosphate compared to 0 mM phosphate treatment. | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 6 | Expression of FGF23 mRNA in human osteoblast-like bone cells, quantitated by real-time RT-PCR, increased with increasing extracellular phosphate and was 2-fold higher in cells treated with 2 mM extracellular phosphate compared to 0 mM phosphate treatment. | Phosphates | fibroblast growth factor 23 | Homo sapiens |
| 7 | The results indicate that FGF23 mRNA expression in bone cells is regulated by extracellular phosphate and by mineralization. | Phosphates | fibroblast growth factor 23 | Homo sapiens |