Pub. Date : 2004 Nov
PMID : 15536457
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A variant 2677A allele of the MDR1 gene affects fexofenadine disposition. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | This study was performed to clarify the effects of major MDR1 gene polymorphisms, including a variant A allele in exon 21, on fexofenadine pharmacokinetics. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | A single oral dose of 180 mg fexofenadine hydrochloride was administered to 33 healthy Korean male volunteers, who were divided into 6 groups based on the MDR1 genotype for the G2677T/A polymorphism in exon 21 and the C3435T polymorphism in exon 26. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |