Title : Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors.

Pub. Date : 2004 Nov 23

PMID : 15534200






1 Functional Relationships(s)
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1 We also show that a small fraction of PTEN molecules is transiently inactivated as a result of oxidation of the essential cysteine residue of this phosphatase in various cell types stimulated with epidermal growth factor, platelet-derived growth factor, or insulin. Cysteine phosphatase and tensin homolog Homo sapiens