Title : Abrogation of hepatocyte apoptosis and early appearance of liver dysplasia in ethanol-fed p53-deficient mice.

Pub. Date : 2004 Dec 3

PMID : 15522206






1 Functional Relationships(s)
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1 In normal mice exposed to a subacute (3 weeks) ethanol intoxication, a significant increase in the number of apoptotic hepatocytes was observed in concomitance with the up-regulation of the mitochondrial superoxide scavenger MnSOD, a reliable indicator of oxidative stress. Superoxides superoxide dismutase 2, mitochondrial Mus musculus