Title : Activation-dependent conformational changes in {beta}-arrestin 2.

Pub. Date : 2004 Dec 31

PMID : 15501822






1 Functional Relationships(s)
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1 Activation of beta-arrestin 2 upon V(2)R-pp binding involves the release of its C terminus, as indicated by exposure of a previously inaccessible cleavage site, one of the polar core residues Arg(394), and rearrangement of its N terminus, as indicated by the shielding of a previously accessible cleavage site, residue Arg(8). (2)r-pp arrestin beta 2 Homo sapiens