Pub. Date : 2004 Dec 6
PMID : 15501038
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | It has been observed that among all these isozymes, hCA V has the lowest affinity for bicarbonate and carbonate (K(i)"s in the range of 82-95 mM), which may represent an evolutionary adaptation of this isozyme to the rather alkaline environment (pH 8.5) within the mitochondria, where hCA V plays important functions in some biosynthetic reactions involving carboxylating enzymes (pyruvate carboxylase and acetyl coenzyme A carboxylase). | Carbonates | carbonic anhydrase 5A | Homo sapiens |
2 | It has been observed that among all these isozymes, hCA V has the lowest affinity for bicarbonate and carbonate (K(i)"s in the range of 82-95 mM), which may represent an evolutionary adaptation of this isozyme to the rather alkaline environment (pH 8.5) within the mitochondria, where hCA V plays important functions in some biosynthetic reactions involving carboxylating enzymes (pyruvate carboxylase and acetyl coenzyme A carboxylase). | Carbonates | carbonic anhydrase 5A | Homo sapiens |