Title : Mechanism by which H-2g, a glucose analog of blood group H antigen, mediates angiogenesis.

Pub. Date : 2005 Mar 15

PMID : 15498849






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previously, we showed that in soluble form, this antigen, Lewis(y)-6/H-5-2 (Le(y)/H) or its glucose analog, 2-fucosyl lactose (H-2g), induced the expression of EC intercellular adhesion molecule-1 (ICAM-1) and leukocyte-endothelial adhesion through the Janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) pathway. Glucose Janus kinase 2 Rattus norvegicus
2 Previously, we showed that in soluble form, this antigen, Lewis(y)-6/H-5-2 (Le(y)/H) or its glucose analog, 2-fucosyl lactose (H-2g), induced the expression of EC intercellular adhesion molecule-1 (ICAM-1) and leukocyte-endothelial adhesion through the Janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) pathway. Glucose Janus kinase 2 Rattus norvegicus