Title : Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts.

Pub. Date : 2004 Oct 15

PMID : 15466888






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Latrunculin B, cytochalasin D and jasplakinolide, which disrupt actin dynamics, prevented insulin- and PDGF-induced actin remodeling but significantly inhibited GLUT4myc translocation only in response to insulin (75-85%, P<0.05), not to PDGF (20-30% inhibition). Cytochalasin D insulin Homo sapiens
2 Latrunculin B, cytochalasin D and jasplakinolide, which disrupt actin dynamics, prevented insulin- and PDGF-induced actin remodeling but significantly inhibited GLUT4myc translocation only in response to insulin (75-85%, P<0.05), not to PDGF (20-30% inhibition). Cytochalasin D insulin Homo sapiens