Title : Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats.

Pub. Date : 2004 Oct 6

PMID : 15464074






2 Functional Relationships(s)
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1 The in vitro experiments showed that the intracellular accumulation of pazufloxacin in adriamycin-resistant human chronic myelogenous leukemia cells (K562/ADR) overexpressing P-glycoprotein was significantly lower than that in human chronic myelogenous leukemia cells (K562/S) not expressing P-glycoprotein. pazufloxacin ATP binding cassette subfamily B member 1 Homo sapiens
2 The in vitro experiments showed that the intracellular accumulation of pazufloxacin in adriamycin-resistant human chronic myelogenous leukemia cells (K562/ADR) overexpressing P-glycoprotein was significantly lower than that in human chronic myelogenous leukemia cells (K562/S) not expressing P-glycoprotein. pazufloxacin ATP binding cassette subfamily B member 1 Homo sapiens