Title : Biphasic induction of heme oxygenase-1 expression in macrophages stimulated with lipopolysaccharide.

Pub. Date : 2004 Nov 1

PMID : 15450936






2 Functional Relationships(s)
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1 Total GSH level decreased markedly (50% of control) by 2 h, began to recover at 4 h, returned to control level by 6 h and increased above the control level during 10-24 h. Collectively, these results indicated that overproduced O2*- depletes GSH and triggers induction of xCT, HO-1, iNOS and HO-1 expression in sequence. Oxygen heme oxygenase 1 Homo sapiens
2 Total GSH level decreased markedly (50% of control) by 2 h, began to recover at 4 h, returned to control level by 6 h and increased above the control level during 10-24 h. Collectively, these results indicated that overproduced O2*- depletes GSH and triggers induction of xCT, HO-1, iNOS and HO-1 expression in sequence. Oxygen heme oxygenase 1 Homo sapiens