Title : A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1.

Pub. Date : 2005 Jan

PMID : 15353403






1 Functional Relationships(s)
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1 Bosentan, a dual-ET receptor antagonist, blocked the increase in THAL eNOS expression caused by high salt (2.66 +/- 0.44 absorbance units with bosentan vs. 5.15 +/- 0.67 for vehicle; P < 0.05). Salts nitric oxide synthase 2 Homo sapiens