Title : Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice.

Pub. Date : 1992 May 28

PMID : 1534660






1 Functional Relationships(s)
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1 Consistent with these observations, treatment of rats with loratadine caused a dose-dependent increase in the rate of two reactions that are catalyzed predominantly by 2B1/2, namely testosterone 16 beta-hydroxylation and 7-pentoxyresorufin O-dealkylation. Testosterone UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus