Title : Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis.

Pub. Date : 2005 Jan 1

PMID : 15345587






1 Functional Relationships(s)
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1 Northern blot analyses showed that the levels of expression of hepcidin mRNA in the liver were generally lower, whereas those of duodenal DMT1, the main transporter for uptake of dietary iron, were higher in the TfR2-mutant mice as compared to the wild-type siblings. Iron solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus