Pub. Date : 2004 Oct 1
PMID : 15345323
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UCP3 and thyroid hormone involvement in methamphetamine-induced hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 2 | Here, we determined the extent of hypothalamic-pituitary-thyroid (HPT) axis and uncoupling protein-3 (UCP3) involvement in methamphetamine (METH)-induced hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 3 | Here, we determined the extent of hypothalamic-pituitary-thyroid (HPT) axis and uncoupling protein-3 (UCP3) involvement in methamphetamine (METH)-induced hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 4 | Here, we determined the extent of hypothalamic-pituitary-thyroid (HPT) axis and uncoupling protein-3 (UCP3) involvement in methamphetamine (METH)-induced hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 5 | Here, we determined the extent of hypothalamic-pituitary-thyroid (HPT) axis and uncoupling protein-3 (UCP3) involvement in methamphetamine (METH)-induced hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 6 | Two hours post-METH treatment, UCP3-/- animal temperature returned to baseline temperatures. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 7 | UCP3-/- mice were also completely protected against the lethal effects of METH, whereas 40% of WT mice succumbed to the hyperthermia. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 8 | Furthermore, the findings indicate that UCP3 plays a major role in the development and maintenance of the hyperthermia induced by METH. | Methamphetamine | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |