Title : Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis.

Pub. Date : 2004 Jul

PMID : 15333773






1 Functional Relationships(s)
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1 A semi-random mutagenesis approach was followed to increase the performance of penicillin acylase PAS2 in the kinetically controlled synthesis of ampicillin from 6-aminopenicillanic acid (6-APA) and activated D-phenylglycine derivatives. Ampicillin glycophorin C (Gerbich blood group) Homo sapiens