| Protein Name | glycophorin C (Gerbich blood group) |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2995 |
| Gene Symbol | GYPC |
| UniProt | P04921 (GLPC_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
511
Total Number of Articles : 536 |
Description |
glycophorin C (Gerbich blood group) |
| Gene Summary |
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
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