Title : Inhibition of polyamine synthesis impairs the secretion of atrial natriuretic peptide.

Pub. Date : 1992 Feb 18

PMID : 1532663






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Quantitation of ANP in plasma by radioimmunoassay indicated that both basal and stimulated levels of ANP in DFMO-treated animals were 21.5% and 50% of those in control rats. Eflornithine natriuretic peptide A Rattus norvegicus
2 Quantitation of ANP in plasma by radioimmunoassay indicated that both basal and stimulated levels of ANP in DFMO-treated animals were 21.5% and 50% of those in control rats. Eflornithine natriuretic peptide A Rattus norvegicus
3 The administration of putrescine restored the levels of basal and AVP-stimulated levels of ANP in plasma which confirmed that DFMO effect on ANP secretion occurred specifically through the polyamine pathway. Eflornithine natriuretic peptide A Rattus norvegicus
4 The administration of putrescine restored the levels of basal and AVP-stimulated levels of ANP in plasma which confirmed that DFMO effect on ANP secretion occurred specifically through the polyamine pathway. Eflornithine natriuretic peptide A Rattus norvegicus