Title : Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination.

Pub. Date : 2004 Aug

PMID : 15298726






1 Functional Relationships(s)
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1 After treatment with these agents, the phosphorylation of protein kinase A, Bcl-2 (Thr56) and Bad (Ser155) was increased, especially in antioxidant (N-acetylcysteine and pyrrolidine dithiocarbamate)-pretreated control cells, but the phosphorylation levels were very low in the antisense-transfected cells. pyrrolidine dithiocarbamic acid BCL2 apoptosis regulator Homo sapiens